The tribological behavior of self-mated Ti3SiC2 in bath of alcohols are investigated at sliding velocity ranging from 0.005 to 0.3 m/s. The results show that the friction coefficient and wear rates of self-mated Ti3SiC2 are reduced greatly under lubrication of alcohols compared to that under dry condition. In alcohols, smooth worn surfaces of Ti3SiC2 can be obtained. The mechanical wear is inhibited and the oxidized Ti and Si species on the worn surface are TiO2 and silica gel. The friction coefficients decrease with carbon numbers and sliding velocity in the n-alcohols. The friction coefficient decrease with sliding velocity in glycol and glycerol as well. The decrease is determined by the increase of the viscosity of alcohols. In glycerol, at 0.1 m/s and 5 N, the friction coefficient of self-mated Ti3SiC2 is 0.08 which is the lowest in this paper. The lubrication regimes are calculated according to classical lubrication theory. At velocity from 0.005 to 0.3 m/s, in all of the alcohols except glycerol, the lambda are below 1 which indicates that the lubrication regime is BL. While in glycerol, the lubrication regimes vary from BL to BL and EHL, then to EHL as the velocity increases.