As an excellent light metal material, titanium alloy has an important application in high technology equipment. In this study, the composite lubrication structure was prepared on the titanium alloy surface by combining the surface texture, thermal oxidation layer, and polytetrafluoroethylene (PTFE)-based lubricating coating. The effect of texture parameters and thermal oxidation layer on the fretting wear behavior of the composite lubrication structure was evaluated under a load of 50 N. The results showed that the PTFE-based lubricating coating on the textured surface showed excellent friction-reduction and anti-wear effect compared with the coating on the single smooth surface and thermal oxidation surface. The introduction of a thermal oxidation layer on the textured surface further improved the fretting wear life of lubrication coating. The friction coefficient and wear rate can be as low as 0.242 and 2.3 x 10(-5) mm(3)center dot N(-1)m(-1), respectively, under dry fretting contact conditions. Compared with the untextured surface, the longevity of the composite lubrication structure is extended by more than 90%.