Piezo/triboelectric nanogenerators (PTNGs) have become the research frontier in many cutting-edge applications, which open up promising possibilities for broad prospects. Fiber materials are the ideal candidate for constructing high-performance PTNGs owing to the compelling features of lightweight, programmable structure, favorable softness, and brilliant breathability. To this end, working mechanisms, material selections, structural designs and fabrication methods of fiber constructed PTNGs are comprehensively presented. An in-depth analysis of emerging applications ranging from intelligent clothing, smart home, and personalized medicine to artificial intelligence is thoughtfully demonstrated. Furthermore, the current problems and potential challenges that hinder their large-scale commercial applications are systematically discussed, laying emphasis on the future development direction of fiber constructed PTNGs. It is expected that this review will supply the audience with some universal strategies and fresh ideas to conduct deep research on fiber constructed PTNGs toward better performance.