Properly cleansing the skin surface plays a crucial role in maintaining the overall body health. Incorporating nanoparticles into skincare products can enhance deep cleansing applications of the skin within the complex system formed by epidermal secretions. This study presents a nanoparticle cleansing tool, namely, patchy structure lignin composite nanoparticles. Lignin, a natural polymer, exhibits the ability to self-assemble into ultrasmall nanosized particles when exposed to a suitable solvent. Meanwhile, the surface of traditional SiO2 clean powder can be modified using rapid grafting techniques to create patchy structures. When these nanoparticles, featuring a patchy microconvex structure, come into contact with the skin, they exhibit stronger friction performance compared to hydrated silica with a smooth surface. As a result, an interlocking state forms among the nanoparticles, facilitating the removal of complex skin systems through the formation of a nanoparticle chain network. This ultimately leaves the skin cleaner and fresher. The unique composition and structure of these patchy composite nanoparticles provide an innovative approach to the development of cleansing products.