To solve the problem of premature failure of the rubber stator of the screw pump due to wear, reduce the frictional resistance torque of the screw pump to solve the problem of difficulty in starting after the shutdown of the screw pump production system in Daqing Oilfield. The effects of micron dot texture and lubricating medium on the tribological properties of 42CrMo metal and acrylonitrile–butadiene rubber mating surfaces were studied by theoretical analysis and tribological tests. The friction coefficient, wear amount, and rubber wear morphology were used as the measurement indexes of drag reduction, wear resistance, and wear degree, respectively. The results showed that the best combination of texture area ratio and the lubricating medium was 10% silicone grease, the friction coefficient and wear amount were reduced by 11% and 10.7%, respectively, compared with untextured, and the main order of chip storage and oil supply effect was 10% > 5% > 15%.