Triboelectric nanogenerator (TENG) has become a promising option for high-entropy energy harvesting and self-powered sensors because of their ability to combine the effects of contact electrification and electrostatic induction to effectively convert mechanical energy into electric power or signals. Here, the theoretical origin of TENG, strategies for high-performance TENG, and its applications in high-entropy energy, self-powered sensors, and blue energy are comprehensively introduced on the basis of the fundamental science and principle of TENG. Besides, a series of work in popular science education for TENG that includes numerous scientific and technological products from our science education base, Maxwell Science+, is emphatically introduced. This topic provides an angle and notable insights into the development of TENG.